STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_283060BolA like protein; Belongs to the BolA/IbaG family. (108 aa)    
Predicted Functional Partners:
ACA1_178080
Uncharacterized protein; Belongs to the BolA/IbaG family.
   
 
 0.910
ACA1_142010
BolA2 protein; Belongs to the BolA/IbaG family.
   
 
 0.910
ACA1_352420
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 
 0.825
ACA1_048560
Glutaredoxin, putative.
  
 
 0.814
ACA1_126440
Glutaredoxin, putative.
  
 
 0.814
ACA1_109470
Thioredoxin.
  
 
 0.814
ACA1_153190
Ironsulfur cluster assembly accessory subfamily protein.
   
 
 0.532
ACA1_055650
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
    
 
 0.526
ACA1_158800
Iron sulfur assembly protein 1, putative.
   
 
 0.523
ACA1_151250
Glycine cleavage Tprotein (Aminomethyl transferase) domain containing protein.
      
 0.506
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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