STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_279390Helicase C-terminal domain containing protein, putative. (725 aa)    
Predicted Functional Partners:
ACA1_256390
Histidinol dehydrogenase; Belongs to the HisA/HisF family.
  
 
 0.932
ACA1_184770
Histidinolphosphate transaminase.
  
 
 0.932
ACA1_185170
Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.
  
 
 0.932
ACA1_167820
Tryptophan synthase subunit beta, putative.
  
  
 0.775
ACA1_283560
Tryptophan synthase alpha chain, putative.
  
  
 0.775
ACA1_283510
Indole3-glycerol phosphate synthase.
  
  
 0.700
ACA1_233850
PxPhosphoserine phosphatase.
  
  
 0.663
ACA1_192970
Basic helixloop-helix (BHLH) family protein.
  
 
 0.641
ACA1_270320
Histidine triad domain containing protein.
  
 
 0.641
ACA1_069080
RanBP2-type domain-containing protein.
  
 
 0.641
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.