STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_111060Xtp3transactivated protein, putative. (249 aa)    
Predicted Functional Partners:
ACA1_191030
CUE domain containing protein.
   
 0.936
ACA1_362540
Zinc finger, C3HC4 type (RING finger) domain containing protein.
   
 0.936
ACA1_106810
FHA domain containing protein.
   
 0.936
ACA1_116690
Uncharacterized protein.
    
 0.933
ACA1_169060
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.933
ACA1_290540
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
    
 0.933
ACA1_058840
Heat shock protein gp96, putative.
   
 
 0.795
ACA1_079160
Hint module protein.
    
  0.764
ACA1_256410
ATPase, AAA domain containing protein.
    
 0.760
ACA1_033500
ATPase, AAA domain containing protein.
    
 0.760
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.