STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_052210RasGEF domain containing protein. (363 aa)    
Predicted Functional Partners:
ACA1_044720
Fbox domain containing protein.
  
 
  0.484
ACA1_179140
Ras subfamily protein.
  
 
  0.465
ACA1_281300
Ras subfamily protein.
  
 
  0.462
ACA1_103990
GTPase activating protein Sar1, putative.
  
 
 
 0.422
ACA1_073470
SH3 domain containing protein.
    
 0.422
ACA1_388510
SH3 domain containing protein.
   
 0.411
ACA1_146260
SH3 domain containing protein.
   
 0.411
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.