STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_279770Molybdenum cofactor biosynthesis protein A, putative. (561 aa)    
Predicted Functional Partners:
ACA1_113920
Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
 0.901
ACA1_301690
Gephyrin, putative.
 
 0.850
ACA1_157550
Haloacid dehalogenaselike hydrolase domain containing protein.
  
    0.761
ACA1_055490
ThiF domain containing protein.
  
 
 0.703
ACA1_279780
Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by by the MOCS3 homolog. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
     
 0.683
ACA1_260020
Coronin; Belongs to the WD repeat coronin family.
    
 0.647
ACA1_238390
Coronin; Belongs to the WD repeat coronin family.
    
 0.647
ACA1_333350
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
    
  0.642
ACA1_054310
Nitrate reductase, putative.
     
 0.569
ACA1_373710
Rhodanese domain-containing protein.
     
 0.567
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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