STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_282370Cholestenol delta-isomerase. (227 aa)    
Predicted Functional Partners:
ACA1_035520
SterolC5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.950
ACA1_220070
Ergosterol biosynthesis erg4/erg24 family protein.
   
 
 0.928
ACA1_360510
4alpha-methyl-sterol C4-methyl-oxidase; Belongs to the sterol desaturase family.
   
 
 0.927
ACA1_237870
Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
    
 0.909
ACA1_193300
Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
    
 0.909
ACA1_232690
Vacuolar proton pump d subunit, putative.
    
 
 0.697
ACA1_175060
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
 
 0.636
ACA1_150590
Vacuolar ATP synthase subunit F, putative.
    
 
 0.587
ACA1_144210
Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.
    
 
 0.558
ACA1_157860
FAD binding domain containing protein.
   
  
 0.408
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.