STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_195230DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. (1400 aa)    
Predicted Functional Partners:
ACA1_180170
RNA-binding domain-containing protein.
   
 0.954
ACA1_364250
3' exoribonuclease family, domain 1 domain containing protein.
   
 0.954
ACA1_171650
Exosome component 7, putative.
   
 0.953
ACA1_258700
Exosc8 protein.
   
 0.951
ACA1_061690
3' exoribonuclease family, domain 1 domain containing protein.
   
 0.949
ACA1_073070
Exosome component 3, putative.
   
 0.949
ACA1_204440
Uncharacterized protein.
   
 0.902
ACA1_360300
3' exoribonuclease family, domain 1 domain containing protein.
   
 0.867
ACA1_291020
Exosome complex exonuclease rrp41, putative.
   
 0.867
ACA1_287750
Sas10/Utp3/C1D family protein.
   
 
 0.864
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.