STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_054370Prolyl 4hydroxylase, alpha subunit. (231 aa)    
Predicted Functional Partners:
ACA1_176080
Leucine rich repeat domain containing protein.
   
 
 0.815
ACA1_109790
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
      
 0.451
ACA1_374120
Protein disulfide-isomerase.
    
 0.422
ACA1_374090
Protein disulfide-isomerase.
    
 0.422
ACA1_244880
Thioredoxin domain containing protein.
    
 0.422
ACA1_305150
Protein disulfide isomerase associated 4, putative; Belongs to the protein disulfide isomerase family.
    
 0.422
ACA1_060030
Thioredoxin domain containing protein.
    
 0.422
ACA1_267190
Thioredoxin domain containing protein.
    
 0.422
ACA1_144370
Ribosomal_L7Ae domain-containing protein.
    
 0.422
ACA1_030810
Thioredoxin domain containing protein.
    
 0.422
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.