STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_225900General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (465 aa)    
Predicted Functional Partners:
ACA1_391550
Ssl1like protein.
   
 0.973
ACA1_267310
PHDfinger domain containing protein.
    
  0.969
ACA1_171520
DNA repair helicase rad25 subfamily protein.
  
 0.966
ACA1_058750
Nucleotide excision repair protein, putative.
    
 0.959
ACA1_278190
CDK-activating kinase assembly factor MAT1 protein.
    
 0.959
ACA1_364240
Cyclin, Nterminal domain containing protein; Belongs to the cyclin family.
    
 0.957
ACA1_326090
Uncharacterized protein.
    
 0.950
ACA1_087480
Transcription factor iia, alpha/beta subunit protein.
    
 0.943
ACA1_020820
TATAbox-binding protein.
    
 0.937
ACA1_218440
RNA polymerase Rpb3/Rpb11 dimerization domain containing protein.
    
 0.931
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.