STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_142390Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (503 aa)    
Predicted Functional Partners:
ACA1_095900
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
ACA1_068670
Dihydrolipoyl dehydrogenase.
 
 0.999
ACA1_062090
Dihydrolipoamide dehydrogenase.
 
 0.991
ACA1_183620
Citrate synthase; Belongs to the citrate synthase family.
  
 0.990
ACA1_278810
Soluble pyridine nucleotide transhydrogenase.
 
 0.986
ACA1_359750
Succinyl coenzyme A synthetase alpha subunit; Belongs to the succinate/malate CoA ligase alpha subunit family.
 
 0.982
ACA1_058740
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.981
ACA1_268920
Oxoglutarate dehydrogenase (Succinyltransferring), E1 component, putative.
  
 0.979
ACA1_292910
Branched-chain alpha-KETO ACID decarboxylase E1 beta subunit, putative.
 0.973
ACA1_019150
Protein-serine/threonine kinase.
    
 0.968
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.