STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_322700GTPase-activator protein for Ras family GTPase. (717 aa)    
Predicted Functional Partners:
ACA1_051830
Mitotic spindle checkpoint protein MAD2, putative.
   
 0.637
ACA1_094950
Protein kinase domain containing protein.
   
 0.579
ACA1_088980
Mad3/BUB1 region 1 family protein.
   
 0.579
ACA1_283080
Anaphase promoting complex subunit 1, putative.
    
 0.567
ACA1_073040
WD domain, G-beta repeat-containing protein.
    
 0.553
ACA1_180640
Tetratricopeptide repeat domain containing protein.
    
  0.549
ACA1_014510
Tetratricopeptide repeat domain containing protein.
    
  0.541
ACA1_277910
Anaphasepromoting complex subunit 2 isoform 2, putative; Belongs to the cullin family.
    
  0.540
ACA1_149800
Tetratricopeptide repeat domain containing protein.
    
  0.540
ACA1_279750
WH1 domain containing protein.
    
 0.526
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.