STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_144380Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1378 aa)    
Predicted Functional Partners:
ACA1_287780
IWS1 Cterminus domain containing protein.
   
 0.998
ACA1_111900
Global transcription factor, putative.
   
 0.968
ACA1_190240
Rtt106 domain-containing protein.
   
 0.962
ACA1_169330
RNA polymerase Rpb5, Cterminal domain containing protein.
    
 0.958
ACA1_291620
DNAdirected RNA polymerase II subunit rpb4, putative.
    
 0.953
ACA1_048550
Tetratricopeptide repeat domain containing protein.
   
 0.937
ACA1_190750
DNAdirected RNA polymerase II subunit RPB7, putative.
    
 0.934
ACA1_234280
Uncharacterized protein.
   
 0.923
ACA1_158460
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.923
ACA1_142400
Plus3 domain containing protein.
   
 
 0.923
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.