STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_072330Ubiquitinlike modifier-activating enzyme 1, putative. (1042 aa)    
Predicted Functional Partners:
ACA1_318550
HECTdomain (Ubiquitin-transferase) domain containing protein.
   
 0.969
ACA1_052770
Ubiquitinconjugating enzyme subfamily protein.
   
 0.899
ACA1_390500
Ubiquitinconjugating enzyme subfamily protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.828
ACA1_040830
Ubiquitinconjugating enzyme protein E2, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.828
ACA1_106730
Ser/Thr phosphatase family protein, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.824
ACA1_267240
Ubiquitinprotein ligase; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.764
ACA1_051880
Autophagy-related protein.
   
 0.756
ACA1_263910
Autophagy-related protein 3.
    
 0.749
ACA1_138500
Ubiquitinconjugating enzyme subfamily protein.
    
 0.729
ACA1_288000
NEDD8activating enzyme E1 catalytic subunit.
    
0.718
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.