STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_172170WD domain, Gbeta repeat/F-box domain containing protein. (506 aa)    
Predicted Functional Partners:
ACA1_368020
RINGbox protein 1, putative.
    
 0.521
ACA1_300720
WD repeat domain 43 isoform 5, putative.
  
     0.505
ACA1_109770
WD40 repeat-containing protein.
  
 
  0.502
ACA1_331480
Membraneassociated ring finger (C3HC4) 2, putative.
  
     0.490
ACA1_198580
Transducin family protein.
  
     0.452
ACA1_053630
Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
  
 
   0.430
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.