STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_173650HEAT repeat domain containing protein. (1074 aa)    
Predicted Functional Partners:
ACA1_164370
Zinc finger domain containing protein.
    
 
 0.708
ACA1_171650
Exosome component 7, putative.
   
 
  0.611
ACA1_180170
RNA-binding domain-containing protein.
   
 
  0.600
ACA1_258700
Exosc8 protein.
   
 
  0.592
ACA1_364250
3' exoribonuclease family, domain 1 domain containing protein.
   
 
  0.591
ACA1_061690
3' exoribonuclease family, domain 1 domain containing protein.
   
 
  0.587
ACA1_073070
Exosome component 3, putative.
   
 
  0.569
ACA1_091430
Znfinger in Ran binding protein and others domain containing protein.
   
 0.555
ACA1_144160
Nucleoporin autopeptidase.
    
 0.485
ACA1_260190
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.448
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.