STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_173980OTU family cysteine protease. (393 aa)    
Predicted Functional Partners:
ACA1_318550
HECTdomain (Ubiquitin-transferase) domain containing protein.
      
 0.525
ACA1_216430
Ubiquitin carboxyl-terminal hydrolase.
   
  
 0.498
ACA1_232670
BAH domain containing protein.
   
 
 0.480
ACA1_293860
Ubiquitin carboxyl-terminal hydrolase.
   
  
 0.472
ACA1_378160
Ubiquitin carboxyl-terminal hydrolase.
      
 0.467
ACA1_178540
Ubiquitin carboxyl-terminal hydrolase.
      
 0.467
ACA1_074760
Signalosome complex protein.
   
  
 0.454
ACA1_190280
Ubiquitinyl hydrolase 1.
      
 0.424
ACA1_107530
Zn-finger in ubiquitin-hydrolases and other protein.
      
 0.424
ACA1_064860
Ubiquitin thioesterase otubainlike, putative.
    
 
 0.403
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.