STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_170670FRAP-related family protein. (583 aa)    
Predicted Functional Partners:
ACA1_004200
Serine-protein kinase ATR family protein; Belongs to the PI3/PI4-kinase family.
 
     0.943
ACA1_351280
3'5' exonuclease domain containing protein.
   
 0.942
ACA1_394580
3'5' exonuclease domain containing protein.
   
 0.942
ACA1_331590
ATPdependent DNA helicase, RecQ subfamily protein.
   
 0.942
ACA1_376610
DEAD/DEAH box helicase domain containing protein.
   
 0.936
ACA1_018990
Subunit of DNA polymerase II.
    
 0.855
ACA1_064360
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.834
ACA1_061390
FATC domain containing protein; Belongs to the PI3/PI4-kinase family.
   
0.824
ACA1_061400
TAN domain-containing protein.
   
 0.824
ACA1_175040
Rad17 cell cycle checkpoint protein.
   
 0.791
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.