STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_272850PH domain containing protein. (235 aa)    
Predicted Functional Partners:
ACA1_326770
SH3 domain containing protein.
   
 0.982
ACA1_321190
Adaptin earbinding coat-associated protein 2 (NECAP-2) isoform 2, putative.
    
 0.973
ACA1_358660
SH3 domain containing protein.
    
 0.946
ACA1_107430
RhoGEF domain containing protein.
    
 0.946
ACA1_112020
RhoGEF domain containing protein.
    
 0.946
ACA1_175570
RhoGEF domain containing protein.
    
0.946
ACA1_363740
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.897
ACA1_160760
Clathrin coat assembly protein AP50, putative.
    
 0.885
ACA1_160880
Clathrin adaptor complex small chain subfamily protein.
    
 0.885
ACA1_217370
Adaptorrelated protein complex 1, beta 1 subunit, isoform 2, putative.
    
 0.884
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.