STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_172850DNA mismatch repair protein msh2, putative. (961 aa)    
Predicted Functional Partners:
ACA1_128040
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.982
ACA1_115690
DNA mismatch repair protein, C-terminal domain containing protein.
 
 0.964
ACA1_149810
DNA mismatch repair protein, Cterminal domain containing protein.
 
 0.963
ACA1_173950
XPG Iregion domain containing protein.
   
 0.963
ACA1_089000
MutS domain containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.952
ACA1_340910
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.951
ACA1_060740
Uncharacterized protein.
   
 0.924
ACA1_031570
DNA mismatch repair protein msh2, putative.
  
  
 
0.906
ACA1_195260
MutL dimerization domain containing protein.
  
 0.894
ACA1_056970
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.835
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.