STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_027810YTH domain-containing protein. (774 aa)    
Predicted Functional Partners:
ACA1_042680
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
    
 
 0.967
ACA1_369920
Cleavage and polyadenylation specificity factor subunit 2.
    
 
 0.965
ACA1_374710
WD domain, G-beta repeat-containing protein.
    
 
 0.963
ACA1_217700
Tetratricopeptide repeat domain containing protein.
    
 
 0.961
ACA1_130520
CPSF A subunit region protein.
    
 
 0.957
ACA1_261450
TrkA Cterminal domain containing protein.
   
 
 0.872
ACA1_155210
Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.
    
 
 0.832
ACA1_130580
Zinc finger, c2h2 type domain containing protein.
   
 
 0.794
ACA1_388780
EGFlike domain containing protein.
   
 
 0.683
ACA1_388770
Poly(A) polymerase central domain containing protein.
   
 
 0.683
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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