STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_173240Poly [ADP-ribose] polymerase. (1093 aa)    
Predicted Functional Partners:
ACA1_396690
ATPdependent DNA helicase ii, 70 kDa subunit (Ku70) superfamily protein.
    
 
 0.626
ACA1_043650
Poly(Adpribose) glycohydrolase.
  
 
 0.625
ACA1_043640
Poly ADP-ribose glycohydrolase (PARG) protein, putative.
  
 
 0.612
ACA1_061630
Poly(Adpribose) glycohydrolase, putative.
  
 
 0.606
ACA1_185730
Poly (ADPribose) glycohydrolase.
  
 
 0.602
ACA1_182790
ATPdependent DNA helicase.
   
 
 0.601
ACA1_265900
Poly glycohydrolase family protein.
  
 
 0.596
ACA1_173950
XPG Iregion domain containing protein.
   
 0.561
ACA1_374140
BRCA1 C Terminus (BRCT) domain containing protein.
    
 
 0.510
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.