STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_173790Nicotinamide-nucleotide adenylyltransferase. (240 aa)    
Predicted Functional Partners:
ACA1_325420
Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
    
 0.978
ACA1_174190
Nicotinate phosphoribosyltransferase.
  
 
 0.967
ACA1_171280
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
 
 0.967
ACA1_116500
NAD(+)/NADH kinase.
  
 
 0.947
ACA1_033640
Ser/Thr phosphatase family protein.
     
  0.932
ACA1_385750
Nicotinamide-nucleotide adenylyltransferase/ nicotinate-nucleotide adenylyltransferase, putative.
  
  
 
0.909
ACA1_356920
Hydrolase, NUDIX domain containing protein; Belongs to the Nudix hydrolase family.
    
 0.909
ACA1_143650
Hydrolase, NUDIX domain containing protein; Belongs to the Nudix hydrolase family.
    
 0.909
ACA1_013640
Hydrolase, NUDIX, putative.
    
 0.909
ACA1_257300
Nicotinamide-nucleotide adenylyltransferase.
  
  
 
0.908
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.