STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACA1_295800Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (478 aa)    
Predicted Functional Partners:
ACA1_292910
Branched-chain alpha-KETO ACID decarboxylase E1 beta subunit, putative.
 0.999
ACA1_068670
Dihydrolipoyl dehydrogenase.
  
 0.994
ACA1_252460
Isovaleryl Coenzyme A dehydrogenase.
   
 0.976
ACA1_095900
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.969
ACA1_268920
Oxoglutarate dehydrogenase (Succinyltransferring), E1 component, putative.
 
 0.959
ACA1_022330
Carbamoylphosphate synthase L chain, ATP-binding, putative.
  
 0.958
ACA1_384630
Short/branched chain specific acylCoA dehydrogenase, mitochondrial, putative.
   
 0.953
ACA1_283230
Oxoglutarate dehydrogenase (Succinyltransferring), E1 component, putative.
 
 0.949
ACA1_315070
Isobutyryl-CoA dehydrogenase, putative.
   
 0.947
ACA1_062090
Dihydrolipoamide dehydrogenase.
  
 0.946
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.