Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00018Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50. (96 aa)    
Predicted Functional Partners:
D920_00017
Toxin-antitoxin system, antitoxin component, AbrB family; Psort location: Cytoplasmic, score: 7.50.
 
     0.993
D920_00202
Addiction module antitoxin, RelB/DinJ family; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.989
D920_02727
Prevent-host-death family protein; KEGG: tgr:Tgr7_1341 0.0038 CheA signal transduction histidine kinase; K03407 two-component system, chemotaxis family, sensor kinase CheA; Psort location: Cytoplasmic, score: 7.50.
 
 
 
 0.966
D920_02933
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
   
 
 0.954
D920_00229
Toxin-antitoxin system, antitoxin component, AbrB domain protein.
       0.923
D920_00921
Toxin-antitoxin system, toxin component, MazF family; Toxic component of a type II toxin-antitoxin (TA) system.
     
 0.919
D920_02045
DNA-binding helix-turn-helix protein; KEGG: sgg:SGGBAA2069_c10720 0.0057 transcriptional regulator.
     
 0.906
D920_03032
Toxin-antitoxin system, toxin component, MazF family; KEGG: efu:HMPREF0351_10520 2.3e-49 chpA; ChpA/MazF transcriptional modulator; K07171 mRNA interferase; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.904
D920_00390
KEGG: efc:EFAU004_00510 3.9e-47 toxin-antitoxin system, toxin component, MazF family K07171.
 
   
 0.903
D920_00464
DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.901
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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