Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00076Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55. (1068 aa)    
Predicted Functional Partners:
D920_00135
YD repeat protein; KEGG: phu:Phum_PHUM617500 0.0010 type II transmembrane protein, putative; Psort location: Cellwall, score: 9.20.
  
  
 0.974
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.923
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.900
D920_02190
Rhamnogalacturonan acetylesterase RhgT family protein; KEGG: efc:EFAU004_02549 8.6e-52 GDSL-like Lipase/Acylhydrolase.
  
 
 0.898
D920_02838
GDSL-like protein; KEGG: efc:EFAU004_01190 5.5e-121 GDSL-like lipase/acylhydrolase; Psort location: CytoplasmicMembrane, score: 9.55.
  
 
 0.898
D920_02541
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.87.
  
  
 0.870
smc
Segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
 
 0.869
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.863
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
     
 0.862
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.854
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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