Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00154Hypothetical protein. (73 aa)    
Predicted Functional Partners:
D920_00155
Addiction module toxin, RelE/StbE family; KEGG: hip:CGSHiEE_07380 0.00026 glyS; glycyl-tRNA synthetase subunit beta K06218.
     
 0.999
D920_00018
Addiction module toxin, RelE/StbE family; Psort location: Cytoplasmic, score: 7.50.
     
 0.885
D920_02296
Metallo-beta-lactamase domain protein; KEGG: efi:OG1RF_10969 7.1e-112 beta-lactamase; Psort location: Cytoplasmic, score: 7.50.
     
 0.874
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
       0.857
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.842
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.840
D920_02118
KEGG: lra:LRHK_15 2.1e-57 yfkM; general stress protein 18; K05520 protease I; Psort location: Cytoplasmic, score: 7.50.
       0.830
D920_02672
Toxin-antitoxin system, toxin component, RelE family.
       0.822
hisS
histidine--tRNA ligase; KEGG: efu:HMPREF0351_12435 3.8e-207 hisS; histidine--tRNA ligase K01892; Psort location: Cytoplasmic, score: 10.00.
       0.819
D920_02443
DnaD domain protein; KEGG: ssr:SALIVB_1214 1.6e-11 tpiA; triosephosphate isomerase K02086; Psort location: Cytoplasmic, score: 7.50.
  
    0.818
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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