Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00189Hypothetical protein. (223 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.966
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.964
D920_00192
DNA-binding helix-turn-helix protein; KEGG: mpx:MPD5_0532 1.8e-10 SOS-response repressor and protease LexA; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.957
D920_01488
DNA-binding helix-turn-helix protein; KEGG: cce:Ccel_3317 9.2e-08 XRE family transcriptional regulator; K01356 repressor LexA; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.957
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.938
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.933
D920_02534
KEGG: efu:HMPREF0351_11245 1.1e-74 comEB; competence protein ComEB K01493; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.924
D920_02535
comEA protein; KEGG: has:Halsa_0780 3.1e-08 glycogen/starch synthase K00703; Psort location: CytoplasmicMembrane, score: 9.96.
  
  
 0.924
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.919
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
     
 0.904
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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