Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00286Hypothetical protein. (200 aa)    
Predicted Functional Partners:
D920_00287
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.997
D920_00288
Hypothetical protein; Psort location: Extracellular, score: 8.91.
 
   
 0.996
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
       0.963
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
       0.902
D920_00099
Helicase protein; KEGG: afm:AFUA_7G05530 7.9e-43 DEAD/DEAH box helicase K01529; Psort location: Cytoplasmic, score: 7.50.
       0.882
D920_00164
Fic family protein; KEGG: yey:Y11_23931 0.00019 type I restriction-modification system,specificity subunit S; Psort location: Cytoplasmic, score: 7.50.
 
    0.877
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.864
D920_00008
Hypothetical protein; KEGG: dan:Dana_GF13333 2.6e-12 GF13333 gene product from transcript GF13333-RA; K00907 myosin-light-chain kinase; Psort location: Cytoplasmic, score: 7.50.
 
     0.854
D920_00289
Hypothetical protein.
 
     0.854
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.850
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.