Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00338Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (232 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.995
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.995
D920_00340
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.995
D920_00341
Stage 0 sporulation protein J; KEGG: pub:SAR11_0354 5.8e-46 parB; chromosome partitioning protein K03497; Psort location: Cytoplasmic, score: 9.97; Belongs to the ParB family.
       0.995
D920_00342
KEGG: ccm:Ccan_17350 9.5e-69 Sporulation initiation inhibitor protein soj K03496; Psort location: CytoplasmicMembrane, score: 8.78.
       0.995
rsmG
16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.990
D920_00335
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efc:EFAU004_02853 4.2e-178 histidine kinase; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.967
D920_01377
Putative Xaa-Pro dipeptidase; KEGG: efu:HMPREF0351_10775 6.8e-162 pepQ; M24B family Xaa-Pro dipeptidase K01262; Psort location: Cytoplasmic, score: 9.97.
       0.967
D920_00012
Hypothetical protein; KEGG: lbi:LEPBI_II0025 6.8e-07 ATPase, ParA family K03496.
       0.911
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.903
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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