Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_00372Pyruvate oxidase; KEGG: efu:HMPREF0351_10017 4.4e-254 poxB; pyruvate oxidase K00158; Psort location: CytoplasmicMembrane, score: 8.78; Belongs to the TPP enzyme family. (598 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.999
D920_00737
Alpha-acetolactate decarboxylase; KEGG: efu:HMPREF0351_11759 2.3e-83 alsD; acetolactate decarboxylase K01575; Psort location: Cytoplasmic, score: 7.50; Belongs to the alpha-acetolactate decarboxylase family.
 
  
 0.994
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.994
D920_02472
KEGG: efu:HMPREF0351_11294 8.3e-173 ilvE; branched-chain-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.990
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.985
phnW
2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
 
 0.978
D920_00763
KEGG: efc:EFAU004_01784 9.9e-193 NADP-specific glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.974
D920_00373
Metal cation transporter, ZIP family; KEGG: smm:Smp_146170 1.3e-34 DNA polymerase epsilon catalytic subunit; K02324 DNA polymerase epsilon subunit 1; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.972
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
  
 
 0.972
D920_00419
KEGG: efc:EFAU004_02122 9.7e-163 L-lactate oxidase K10530; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.962
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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