Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00405Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: apv:Apar_1344 4.7e-37 peptidoglycan glycosyltransferase K05364; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. (395 aa)    
Predicted Functional Partners:
D920_01360
KEGG: efu:HMPREF0351_10791 0. pbpA; penicillin-binding protein 1 K12556; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 0.998
D920_02688
Penicillin-binding protein, transpeptidase domain protein; KEGG: efu:HMPREF0351_10994 0. pbp2B; penicillin-binding protein K00687; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 0.998
D920_00406
Transcriptional regulator, Spx/MgsR family; KEGG: efu:HMPREF0351_10569 1.0e-39 arsC; arsenate reductase; Belongs to the ArsC family.
     
 0.997
D920_00407
Glycine cleavage H-protein; KEGG: mpx:MPD5_0506 7.5e-21 arsenate reductase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.997
divIB
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 0.997
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.996
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
 
   
 0.995
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
 
 
 0.993
D920_01515
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.993
D920_01520
KEGG: efc:EFAU004_02618 2.5e-242 serine/threonine-protein kinase K08884; Psort location: CytoplasmicMembrane, score: 8.78.
  
 
 0.993
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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