Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00455HTH domain protein. (331 aa)    
Predicted Functional Partners:
D920_00456
Transcriptional regulator, effector binding domain protein.
 
  
 0.989
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.945
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
     
 0.923
D920_00378
Transcriptional regulator, effector binding domain protein; KEGG: pjd:Pjdr2_5363 1.6e-09 AraC family transcriptional regulator K13530; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.916
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.906
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
  
  
 0.886
D920_00418
N-6 DNA Methylase; KEGG: smn:SMA_1208 6.8e-59 hsdM; type I restriction-modification system, DNA-methyltransferase subunit M; K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.880
D920_03097
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.879
D920_01185
Hypothetical protein; KEGG: pfe:PSF113_4044 0.00018 glyoxalase bleomycin resistance protein dioxygenase K04750; Psort location: Cytoplasmic, score: 7.50.
     
 0.878
D920_01394
Methyltransferase domain protein; KEGG: efc:EFAU004_00735 1.1e-97 O-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.874
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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