Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00460Hypothetical protein. (82 aa)    
Predicted Functional Partners:
D920_03068
Transporter, major facilitator family protein; KEGG: ssr:SALIVB_1450 8.0e-88 coaE; Dephospho-CoA kinase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.988
D920_03066
Hypothetical protein; KEGG: efu:HMPREF0351_10561 4.5e-55 superoxide dismutase.
       0.928
D920_01101
KEGG: efi:OG1RF_10140 3.9e-150 adh3; putative alcohol dehydrogenase (NADP(+)); Psort location: Cytoplasmic, score: 9.97.
       0.922
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
       0.885
D920_00918
Phage infection protein; KEGG: edi:EDI_048910 2.3e-14 intracellular protein transport protein USO1; Psort location: CytoplasmicMembrane, score: 10.00.
       0.864
D920_00789
Transporter, major facilitator family protein; KEGG: ssr:SALIVB_1450 3.2e-116 coaE; Dephospho-CoA kinase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.828
D920_02126
Cation diffusion facilitator family transporter; KEGG: bqy:MUS_3253 5.4e-13 cation efflux system protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.805
D920_02423
Cation diffusion facilitator family transporter; KEGG: msi:Msm_0789 3.8e-33 cation efflux system protein (zinc/cadmium/cobalt); Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.805
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.740
D920_02673
Hypothetical protein; KEGG: cdb:CDBH8_1365 1.5e-26 putative oxidoreductase.
       0.673
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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