Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_00481KEGG: efu:HMPREF0351_10655 5.1e-70 phosphoglycerate mutase K15634; Psort location: Cytoplasmic, score: 7.50. (195 aa)    
Predicted Functional Partners:
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
     
 0.980
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
     
 0.972
D920_02032
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.7e-14 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.970
D920_00793
Pyruvate kinase; KEGG: efc:EFAU004_01291 6.6e-299 Pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.961
D920_01579
Nitroreductase family protein; KEGG: efu:HMPREF0351_12619 1.3e-89 NADH dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.954
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.949
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
   
 0.947
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.946
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
     
 0.936
D920_00538
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.933
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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