Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00502FtsK/SpoIIIE family protein; KEGG: ppo:PPM_p0073 3.1e-06 topB; DNA topoisomerase III; Psort location: CytoplasmicMembrane, score: 9.96. (451 aa)    
Predicted Functional Partners:
D920_00503
Replication initiation factor; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.993
D920_01127
DNA-binding helix-turn-helix protein; KEGG: fnu:FN0522 0.00098 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.985
D920_01935
DNA-binding helix-turn-helix protein; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.985
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.984
D920_02367
Hypothetical protein; KEGG: ppu:PP_2945 0.0026 sensor histidine kinase/response regulator; K02482 two-component system, NtrC family, sensor kinase.
  
 
 0.982
D920_01520
KEGG: efc:EFAU004_02618 2.5e-242 serine/threonine-protein kinase K08884; Psort location: CytoplasmicMembrane, score: 8.78.
     
 0.981
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.976
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.5e-16 fadD; long-chain-fatty-acid--CoA ligase K03743; Belongs to the CinA family.
     
 0.973
D920_00135
YD repeat protein; KEGG: phu:Phum_PHUM617500 0.0010 type II transmembrane protein, putative; Psort location: Cellwall, score: 9.20.
  
  
 0.971
D920_02532
Metallo-beta-lactamase domain protein; KEGG: zga:zobellia_1566 0.0040 metallohydrolase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.971
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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