Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_00505Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (231 aa)    
Predicted Functional Partners:
D920_00516
Integrase core domain protein; KEGG: ebe:B21_03481 8.5e-29 insI-1; IS30 transposase, N-ter fragment.
     
 0.874
D920_00217
Peptidase, M23 family; KEGG: efu:HMPREF0351_12843 1.6e-185 lysozyme; Psort location: CytoplasmicMembrane, score: 9.55.
       0.865
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.865
D920_03065
DNA topoisomerase; KEGG: efu:HMPREF0351_10562 0. topB; DNA topoisomerase TopB K03169; Psort location: Cytoplasmic, score: 9.64.
       0.865
D920_01657
KEGG: efu:HMPREF0351_11046 3.4e-160 alkanal monooxygenase (FMN-linked); Psort location: Cytoplasmic, score: 7.50.
     
 0.856
D920_02148
Muramidase-2; KEGG: efc:EFAU004_02584 5.0e-269 N-acetylmuramoyl-L-alanine amidase; Psort location: Extracellular, score: 9.98.
       0.849
D920_02449
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; KEGG: efc:EFAU004_01007 5.5e-128 N-acetylmuramoyl-L-alanine amidase; Psort location: CytoplasmicMembrane, score: 8.77.
       0.849
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.798
D920_00286
Hypothetical protein.
       0.777
D920_01456
KEGG: apb:SAR116_0666 2.3e-19 DNA repair protein RadC K03630; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0758 family.
       0.772
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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