Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00555Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55. (235 aa)    
Predicted Functional Partners:
D920_00759
Hypothetical protein; KEGG: efc:EFAU004_01788 1.1e-152 SAM-dependent methyltransferase K06969.
       0.904
D920_01270
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.904
D920_01271
Phosphocarrier protein HPr; KEGG: efc:EFAU004_01332 5.7e-39 ptsH; phosphocarrier protein HPr K11189; Psort location: Cytoplasmic, score: 10.00.
       0.904
D920_01514
Rod shape-determining protein MreD; Psort location: CytoplasmicMembrane, score: 10.00.
       0.904
D920_01515
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
       0.904
cysS
cysteine--tRNA ligase; KEGG: efc:EFAU004_02655 1.8e-223 cysS; cysteinyl-tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.904
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
       0.904
thrS
threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
       0.896
D920_00793
Pyruvate kinase; KEGG: efc:EFAU004_01291 6.6e-299 Pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
       0.894
D920_02483
tryptophan--tRNA ligase; KEGG: efu:HMPREF0351_11284 1.5e-164 trpS; tryptophan--tRNA ligase K01867; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.886
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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