Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rexPutative redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (211 aa)    
Predicted Functional Partners:
D920_00557
ABC transporter, ATP-binding protein; KEGG: efu:HMPREF0351_12159 9.0e-302 ABC superfamily ATP binding cassette transporter, ABC protein K06158; Psort location: Cytoplasmic, score: 9.67.
     
 0.996
D920_00901
KEGG: efu:HMPREF0351_10204 0. aad; aldehyde-alcohol dehydrogenase K04072; Psort location: Cytoplasmic, score: 9.97; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.992
D920_02309
KEGG: bya:BANAU_2956 0.00013 ytrA; GntR family transcriptional regulator; Psort location: CytoplasmicMembrane, score: 8.16.
       0.989
D920_00525
KEGG: efu:HMPREF0351_10676 1.7e-156 pta; phosphate acetyltransferase K00625; Psort location: Cytoplasmic, score: 7.50.
     
 0.986
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.986
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.983
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.979
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.972
D920_01842
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.967
D920_01845
Adenylate cyclase; KEGG: efu:HMPREF0351_12418 5.7e-55 cyaA; adenylate cyclase; Psort location: Cytoplasmic, score: 7.50.
       0.967
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.