Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00590KEGG: lsl:LSL_1276 5.8e-133 wecB; UDP-N-acetylglucosamine 2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97. (386 aa)    
Predicted Functional Partners:
D920_00589
Nucleotide sugar dehydrogenase; KEGG: bth:BT_0602 1.3e-137 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; K00100; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 0.994
D920_01313
Methyltransferase domain protein; KEGG: efu:HMPREF0351_10904 4.1e-203 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.986
D920_00588
Polysaccharide biosynthesis protein; KEGG: vfi:VF_0348 2.0e-09 sensor protein UhpB K00936; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.983
D920_00106
Nucleotide sugar dehydrogenase; KEGG: bpf:BpOF4_06560 9.3e-110 UDP-glucose/GDP-mannose dehydrogenase; K02472 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Psort location: Cytoplasmic, score: 9.95.
  
 0.978
D920_00582
NAD dependent epimerase/dehydratase family protein; KEGG: sud:ST398NM01_0168 4.4e-119 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.978
D920_01325
Glycosyltransferase, group 4 family; KEGG: efu:HMPREF0351_10891 8.0e-175 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase K13685; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.973
D920_00578
DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: ctx:Clo1313_3008 1.4e-138 glutamine--scyllo-inositol transaminase; Psort location: Cytoplasmic, score: 9.97; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.971
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.967
D920_00581
KEGG: txy:Thexy_1804 2.2e-147 UDP-glucose 4-epimerase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.957
D920_00586
Hypothetical protein; KEGG: sud:ST398NM01_0171 3.3e-12 Glycosyltransferase.
  
  
 0.956
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.