Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_00625HD domain protein; KEGG: mpx:MPD5_0935 2.8e-181 deoxyguanosine triphosphate triphosphohydrolase K06885; Psort location: Cytoplasmic, score: 7.50. (456 aa)    
Predicted Functional Partners:
D920_00624
Cof-like hydrolase; KEGG: efc:EFAU004_02086 1.7e-117 HAD superfamily hydrolase K07024; Psort location: Cytoplasmic, score: 7.50.
     
 0.998
D920_00626
KEGG: efc:EFAU004_02084 3.8e-81 lipoate-protein ligase A.
  
  
 0.998
D920_00627
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
     
 0.997
rpoE
DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
 
     0.989
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.962
D920_03036
KEGG: efc:EFAU004_02270 2.0e-116 TatD family hydrolase K03424; Psort location: Cytoplasmic, score: 9.97.
  
    0.961
D920_01029
Cof-like hydrolase; KEGG: efc:EFAU004_00141 1.6e-107 HAD superfamily hydrolase K07024; Psort location: Cytoplasmic, score: 7.50.
     
 0.947
purM
KEGG: efc:EFAU004_01107 3.1e-134 Phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 9.97.
  
    0.933
argS
arginine--tRNA ligase; KEGG: efu:HMPREF0351_11691 3.5e-277 argS; arginine--tRNA ligase K01887; Psort location: Cytoplasmic, score: 9.97.
       0.928
purC
KEGG: efc:EFAU004_01112 2.9e-83 purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50; Belongs to the SAICAR synthetase family.
   
   0.927
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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