Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
D920_00698Hypothetical protein. (147 aa)    
Predicted Functional Partners:
D920_00700
Hypothetical protein; KEGG: smp:SMAC_06805 4.8e-11 hypothetical protein; K00728 dolichyl-phosphate-mannose-protein mannosyltransferase.
 
  
 0.999
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
     
 0.986
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
       0.979
D920_02983
TIGR01906 family protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.977
D920_02473
Transporter, small conductance mechanosensitive ion channel MscS family protein; KEGG: mla:Mlab_1701 7.9e-09 phosphoglycerate mutase K01834; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.974
D920_00692
PspC domain protein; KEGG: rer:RER_19410 0.0084 two-component histidine kinase; Psort location: CytoplasmicMembrane, score: 9.55.
 
     0.970
D920_03067
Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 7.50.
 
     0.969
D920_02014
Tex-like protein; KEGG: bur:Bcep18194_A5099 3.1e-166 RNA binding S1 K06959; Psort location: Cytoplasmic, score: 9.97.
       0.967
D920_02015
KEGG: efi:OG1RF_11084 1.0e-46 SprT family protein K03095; Psort location: Cytoplasmic, score: 7.50.
       0.967
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.966
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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