Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
D920_00718KEGG: efc:EFAU004_02003 5.3e-146 thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 9.97. (310 aa)    
Predicted Functional Partners:
D920_00606
Thioredoxin; KEGG: efc:EFAU004_02107 2.2e-46 thioredoxin K03671; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family.
 
 0.998
D920_02731
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.997
D920_00719
Phosphoglucomutase; KEGG: efc:EFAU004_02002 3.6e-259 phosphoglucomutase/phosphomannomutase family protein K01835; Psort location: Cytoplasmic, score: 7.50.
     
 0.996
D920_00720
HTH-type transcriptional repressor CzrA family protein; KEGG: apb:SAR116_2180 6.4e-08 ArsR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
     
 0.996
D920_01967
Pyruvate synthase; KEGG: efu:HMPREF0351_11628 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.996
D920_02347
Thioredoxin; KEGG: efc:EFAU004_02107 8.2e-31 thioredoxin K03671; Psort location: Cytoplasmic, score: 9.67; Belongs to the thioredoxin family.
 
 
 0.995
D920_00707
Hypothetical protein; KEGG: lki:LKI_01225 2.0e-20 LexA repressor K09976; Psort location: CytoplasmicMembrane, score: 9.55.
       0.991
D920_00708
ABC transporter, ATP-binding protein; KEGG: efc:EFAU004_02011 3.1e-260 Multidrug resistance-like ATP-binding protein mdlA K06147; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.990
D920_00709
ABC transporter, ATP-binding protein; KEGG: efi:OG1RF_11442 7.7e-257 mdlB; multidrug ABC superfamily ATP binding cassette transporter, ABC protein K06147; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.988
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
  
 0.987
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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