Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00748Transporter, major facilitator family protein; KEGG: apb:SAR116_1122 1.2e-31 tetracycline resistance protein; Psort location: CytoplasmicMembrane, score: 10.00. (413 aa)    
Predicted Functional Partners:
D920_00747
Transcriptional regulator, MarR family; KEGG: edi:EDI_076200 0.0088 GRIP1-associated protein; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.997
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
 0.987
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
     
 0.981
D920_02739
KEGG: efu:HMPREF0351_11839 3.2e-68 tag; DNA-3-methyladenine glycosylase I K01246.
       0.960
D920_01643
KEGG: vfi:VF_A1053 1.8e-07 MerR family transcriptional regulator; Psort location: Cytoplasmic, score: 7.50.
     
 0.958
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.931
D920_00761
YbaK/EbsC protein; KEGG: bya:BANAU_2580 6.0e-28 yjdI; prolyl-tRNA synthetase K03976; Psort location: Cytoplasmic, score: 7.50; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
     
 0.930
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.926
D920_02423
Cation diffusion facilitator family transporter; KEGG: msi:Msm_0789 3.8e-33 cation efflux system protein (zinc/cadmium/cobalt); Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
     
 0.926
D920_02774
Putative cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
  
 0.913
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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