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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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aroD3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (245 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.999
D920_00759
Hypothetical protein; KEGG: efc:EFAU004_01788 1.1e-152 SAM-dependent methyltransferase K06969.
       0.997
D920_00761
YbaK/EbsC protein; KEGG: bya:BANAU_2580 6.0e-28 yjdI; prolyl-tRNA synthetase K03976; Psort location: Cytoplasmic, score: 7.50; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
     
 0.996
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
   
 0.996
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.996
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
   
 0.995
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
   
 0.994
D920_02086
3-deoxy-7-phosphoheptulonate synthase; KEGG: efc:EFAU004_01582 3.3e-146 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; Psort location: Cytoplasmic, score: 9.97.
     
 0.982
D920_02081
Cell envelope-like function transcriptional attenuator common domain protein; Psort location: CytoplasmicMembrane, score: 9.51.
       0.967
D920_02170
Hypothetical protein; KEGG: pcb:PC000690.00.0 0.0076 hypothetical protein; K10696 E3 ubiquitin-protein ligase BRE1; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0342 family.
       0.967
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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