Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00773Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. (442 aa)    
Predicted Functional Partners:
D920_00772
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.997
D920_00774
Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 7.50.
       0.937
D920_02583
Hypothetical protein; KEGG: efu:HMPREF0351_11193 9.8e-99 dihydrodipicolinate synthase/N-acetylneuraminate lyase.
       0.932
D920_01157
Transcriptional regulator, DeoR family; KEGG: lcb:LCABL_29260 4.6e-21 nadD; Nicotinic acid mononucleotide adenyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.924
D920_02496
Hypothetical protein.
 
     0.918
D920_01453
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.888
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.805
D920_00419
KEGG: efc:EFAU004_02122 9.7e-163 L-lactate oxidase K10530; Psort location: Cytoplasmic, score: 7.50.
       0.786
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
       0.786
D920_01827
KEGG: efc:EFAU004_02455 2.0e-162 L-lactate oxidase; Psort location: Cytoplasmic, score: 7.50.
       0.786
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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