Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
D920_00797Phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (490 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
tal
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.999
D920_00793
Pyruvate kinase; KEGG: efc:EFAU004_01291 6.6e-299 Pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.998
D920_00798
Response regulator ArlR; KEGG: rha:RHA1_ro05622 1.5e-47 response regulator (protein-glutamate methylesterase) K07669; Psort location: Cytoplasmic, score: 9.97.
     
 0.997
rpmF
Ribosomal protein L32; KEGG: apb:SAR116_0011 0.00053 50S ribosomal protein L32 K02911; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bL32 family.
       0.994
D920_00799
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: efu:HMPREF0351_11008 2.1e-229 sensor histidine kinase; Psort location: CytoplasmicMembrane, score: 8.78.
     
 0.994
D920_01623
Transketolase; KEGG: efc:EFAU004_01009 1.5e-274 tkt; transketolase K00615; Belongs to the transketolase family.
  
 
 0.994
D920_02450
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.994
D920_00795
Putative ACR; Psort location: CytoplasmicMembrane, score: 8.16.
       0.991
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 0.989
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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