Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
D920_008152-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (330 aa)    
Predicted Functional Partners:
D920_00814
KEGG: ctc:CTC01841 3.0e-56 PTS system, fructose-specific IIBC component K07035; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.994
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.970
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.952
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.945
D920_00947
PTS system mannose-specific EIIBCA component; KEGG: efu:HMPREF0351_11043 1.3e-222 manP; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02793 PTS system, mannose-specific IIA component; K02794 PTS system, mannose-specific IIB component K02795; Psort location: CytoplasmicMembrane, score: 10.00.
       0.933
D920_01985
PTS system fructose-specific EIIABC component; KEGG: efu:HMPREF0351_11611 4.1e-297 fruAB; PTS system fructose/mannitol (fru) transporter subunit IIABC; K02768 PTS system, fructose-specific IIA component; K02769 PTS system, fructose-specific IIB component K02770; Psort location: CytoplasmicMembrane, score: 10.00.
       0.933
D920_02981
Pyridine nucleotide-disulfide oxidoreductase; KEGG: efc:EFAU004_02225 2.7e-144 ferredoxin--NADP reductase K00384; Psort location: Cytoplasmic, score: 9.97.
     
 0.929
folE
GTP cyclohydrolase I; KEGG: efa:EF3267 1.2e-54 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
     
 0.921
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
     
 0.920
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
     
 0.918
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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