Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
D920_00823Thioredoxin; KEGG: lru:HMPREF0538_20267 6.6e-29 trxA; thioredoxin; Psort location: Cytoplasmic, score: 7.50. (106 aa)    
Predicted Functional Partners:
D920_02731
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.996
D920_00822
KEGG: apb:SAR116_0757 4.6e-05 universal stress protein family protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.995
D920_00824
KEGG: efc:EFAU004_00277 2.1e-183 glutamyl aminopeptidase K01261.
       0.995
D920_00821
tRNA binding domain protein; KEGG: efu:HMPREF0351_10247 8.0e-88 pheT; phenylalanine--tRNA ligase beta subunit K06878; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.991
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.985
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.985
msrB
methionine-R-sulfoxide reductase; KEGG: efu:HMPREF0351_10140 2.5e-61 msrB; peptide-methionine (R)-S-oxide reductase K07305; Psort location: Cytoplasmic, score: 7.50.
  
 0.983
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.982
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.982
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
     
 0.980
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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