Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00915SPFH/Band 7/PHB domain protein; KEGG: bbk:BARBAKC583_0924 1.5e-06 hflK; HflK protein; K04088 membrane protease subunit HflK; Psort location: CytoplasmicMembrane, score: 9.55. (293 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.995
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.991
D920_02357
Hypothetical protein; KEGG: efc:EFAU004_00863 3.5e-46 Flavin reductase-like domain protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.990
D920_01776
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.989
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.988
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.984
D920_01552
KEGG: efc:EFAU004_02646 7.0e-192 peptidase M16 inactive domain protein; Psort location: Cytoplasmic, score: 7.50; overlaps another CDS with the same product name.
  
 0.982
D920_01553
KEGG: efc:EFAU004_02647 1.9e-164 Peptidase M16 inactive domain protein; Psort location: Cytoplasmic, score: 7.50; overlaps another CDS with the same product name.
  
 0.982
D920_02591
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.982
D920_02356
Glyoxalase family protein; KEGG: efi:OG1RF_10247 2.0e-137 gloA; lactoylglutathione lyase K15975; Psort location: Cytoplasmic, score: 7.50.
  
   0.979
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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