Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
D920_00995Cof-like hydrolase; KEGG: efc:EFAU004_00173 1.4e-115 HAD superfamily hydrolase K07024; Psort location: Cytoplasmic, score: 7.50. (257 aa)    
Predicted Functional Partners:
D920_00996
KEGG: efc:EFAU004_00172 9.1e-64 DNA alkylation repair protein.
       0.997
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.991
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
     
 0.991
D920_00993
Hypothetical protein; KEGG: edi:EDI_217850 0.00027 caldesmon; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0342 family.
       0.991
D920_00994
Putative metallophosphoesterase; KEGG: efc:EFAU004_00174 9.6e-124 calcineurin-like phosphoesterase K09769; Psort location: Cytoplasmic, score: 7.50.
       0.991
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
     
 0.991
D920_00990
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.979
D920_00062
Hypothetical protein; KEGG: dda:Dd703_0763 1.9e-10 PTS system beta-glucoside-specific transporter subunit IIABC; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 9.55.
     
 0.935
D920_00484
KEGG: efu:HMPREF0351_10658 2.2e-291 PTS family sucrose porter component IIABC; K02809 PTS system, sucrose-specific IIB component K02810; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.935
D920_00712
KEGG: efu:HMPREF0351_11993 9.2e-261 bglP2; PTS family glucose/glucoside (glc) porter component IIABC; K02755 PTS system, beta-glucosides-specific IIA component; K02756 PTS system, beta-glucosides-specific IIB component K02757; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.935
Your Current Organism:
Enterococcus faecalis 13SDW01
NCBI taxonomy Id: 1260356
Other names: E. faecalis 13-SD-W-01, Enterococcus faecalis 13-SD-W-01
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